inositol 1,4,5 triphosphate [IP3]-3-kinase B (IP3 3-kinase B, IP3K-B, ITPKB)

Function

• IP3K is activated by calmodulin
• form B is much more sensitive to Ca+2/calmodulin than form A

ATP + 1D-myo-inositol 1,4,5-trisphosphate
                   <-->
ADP + 1D-myo-inositol 1,3,4,5-tetrakisphosphate

Structure

belongs to the inositol phosphokinase (IPK) family

Alternative splicing

named isoforms=2

More general terms

• inositol 1,4,5 triphosphate [IP3]-3-kinase

Database

• UniProt: http://www.uniprot.org/uniprot/P27987.html
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:3707
• OMIM: https://mirror.omim.org/entry/147522