rhoA proto-oncogene protein; transforming protein RhoA; H12 (RHOA, ARH12, ARHA, RHO12)

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Function

Cofactor: Mg+2

Structure

  • basic-rich region is essential for yopT recognition & cleavage
  • belongs to the small GTPase superfamily, Rho family

Compartment

Pathology

More general terms

References

  1. UniProt http://www.uniprot.org/uniprot/P61586.html
  2. Atlas of Genetics & Cytogenetics in Oncology & Haematology http://atlasgeneticsoncology.org/genes/RHOAID42107ch3p21.html
  3. OMIM https://mirror.omim.org/entry/165370
  4. Kahn RA, Der CJ, Bokoch GM. The ras superfamily of GTP-binding proteins: guidelines on nomenclature. FASEB J. 1992 May;6(8):2512-3. PMID: https://www.ncbi.nlm.nih.gov/pubmed/1592203
  5. Manser E, Leung T, Salihuddin H, Zhao ZS, Lim L. A brain serine/threonine protein kinase activated by Cdc42 and Rac1. Nature. 1994 Jan 6;367(6458):40-6. PMID: https://www.ncbi.nlm.nih.gov/pubmed/8107774
  6. Entrez Gene http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=387

Database