syntaxin

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Introduction

2 syntaxins A & B are 84% identical & expressed only in the CNS. They may function in docking synaptic vesicles near Ca+2 channels at presynaptic active zones. Syntaxins associate with synaptotagmin.

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References

  1. Sollner T, Whiteheart SW, Brunner M et al SNAP receptors implicated in vesicle targeting and fusion. Nature. 1993 Mar 25;362(6418):318-24. PMID: https://www.ncbi.nlm.nih.gov/pubmed/8455717
  2. Bennett MK, Calakos N, Scheller RH. Syntaxin: a synaptic protein implicated in docking of synaptic vesicles at presynaptic active zones. Science. 1992 Jul 10;257(5067):255-9. PMID: https://www.ncbi.nlm.nih.gov/pubmed/1321498