syntaxin-6 (STX6)

Function

• role in intracellular vesicle trafficking
• binds EEA1
• interacts with VPS45A
• interacts with MARCH2 & MARCH3 (putative)
• interacts with GOPC
• identified in a complex containing STX6, STX13, VAMP4 & VTI1A
• phosphorylated upon DNA damage, probably by ATM or ATR

Structure

• belongs to the syntaxin family
• contains 1 t-SNARE coiled-coil homology domain

Compartment

• Golgi apparatus membrane

More general terms

• syntaxin
• phosphoprotein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:1022
• OMIM: https://mirror.omim.org/entry/603944
• UniProt: http://www.uniprot.org/uniprot/O43752.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=10228