syntaxin-16; syn16 (STX16)

Function

• SNARE involved in a vesicular transport step within the Golgi stack

Structure

• belongs to the syntaxin family
• contains 1 t-SNARE coiled-coil homology domain

Compartment

• Golgi apparatus membrane
• isoform C: cytoplasm

Alternative splicing

named isoforms=4

Expression

ubiquitous

Pathology

• genetic variations in STX16 may be a cause of pseudohypoparathyroidism type 1B

More general terms

• syntaxin
• phosphoprotein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:8675
• OMIM: https://mirror.omim.org/entry/603233
• OMIM: https://mirror.omim.org/entry/603666
• UniProt: http://www.uniprot.org/uniprot/O14662.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=8675