syntaxin-11 (STX11)
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Function
- SNARE that acts to regulate protein transport between late endosomes & the trans-Golgi network
- interacts with the SNARE proteins SNAP-23 & VAMP
Structure
- belongs to the syntaxin family
- contains 1 t-SNARE coiled-coil homology domain
Compartment
- peripheral membrane
- trans-Golgi network membrane
Pathology
- defects in STX11 are the cause of familial hemophagocytic lymphohistiocytosis type 4
More general terms
References
- ↑ UniProt http://www.uniprot.org/uniprot/O75558.html
- ↑ STX11base; STX11 mutation db http://bioinf.uta.fi/STX11base/
- ↑ GeneReviews https://www.genecards.org/cgi-bin/carddisp.pl?gene=STX11
Database
- Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:8676
- OMIM: https://mirror.omim.org/entry/603552
- OMIM: https://mirror.omim.org/entry/605014
- UniProt: http://www.uniprot.org/uniprot/O75558.html
- Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=6810
- Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=8676