interactor protein for cytohesin exchange factors 1 (phosphoinositide- binding protein PIP3-E, IPCEF1, KIAA0403)

Function

• enhances the promotion of guanine-nucleotide exchange by PSCD2 on ARF6 (concentration-dependent) (putative)
• interacts with guanine-nucleotide exchange factors PSCD1, PSCD2, PSCD3 & PSCD4 (putative)

Structure

contains 1 PH domain

Compartment

• cytoplasm (putative)
• cell membrane
• translocated with PSCD2 to the plasma membrane upon epidermal growth factor (EGF) stimulation (putative)

Alternative splicing

named isoforms=2

Notes

uncertain whether Met-1 or Met-29 is the initiator

More general terms

• uncharacterized protein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:2603
• UniProt: http://www.uniprot.org/uniprot/Q8WWN9.html