hyperbaric oxygen
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Introduction
Oxygen at greater than atmospheric pressure that can be applied either to the whole patient inside a pressurized chamber or to a localized area (such as an arm or leg) inside a smaller chamber.
Indications
- poisonings, drug overdose (potentially of benefit)
- carbon monoxide
- cyanide poisoning
- hydrogen sulfide
- brown recluse spider bite
- acetaminophen poisoning
- non healing diabetic foot ulcer (covered by Medicare)[2]
- hyperbaric oxygen decreases amputation rates[3]
- does not decrease need for amputation[6]
Contraindications
- untreated pneumothorax[3]
- recent chemotherapy with doxorubicin or cisplatin[3]
- caution:
- heart failure
- COPD
- other concurrent antineoplastic agent(s)
- has not been proven effective for treating
Adverse effects
- sinus pain
- ear pressure
- arthralgia
- air embolism
- paralysis
- risk of fire
Procedure
- treatment applied in chamber for 1.5-2 hours/day for 20-40 days
More general terms
Additional terms
References
- ↑ Daubert GP, Emergency Medicine, University of California, Davis
- ↑ 2.0 2.1 Geriatrics at your Fingertips, 13th edition, 2011 Reuben DB et al (eds) American Geriatric Society
- ↑ 3.0 3.1 3.2 3.3 Medical Knowledge Self Assessment Program (MKSAP) 16, American College of Physicians, Philadelphia 2012
- ↑ Eskes A, Ubbink DT, Lubbers M, Lucas C, Vermeulen H. Hyperbaric oxygen therapy for treating acute surgical and traumatic wounds. Cochrane Database Syst Rev. 2010 Oct 6;(10):CD008059 PMID: https://www.ncbi.nlm.nih.gov/pubmed/20927771
- ↑ FDA Consumer Update. August 22, 2013 Hyperbaric Oxygen Therapy: Don't Be Misled http://www.fda.gov/ForConsumers/ConsumerUpdates/ucm364687.htm
- ↑ 6.0 6.1 Fedorko L et al. Hyperbaric oxygen therapy does not reduce indications for amputation in patients with diabetes with nonhealing ulcers of the lower limb: A prospective, double-blind, randomized controlled clinical trial. Diabetes Care 2016 Mar; 39:392. PMID: https://www.ncbi.nlm.nih.gov/pubmed/26740639
- ↑ 7.0 7.1 Shapira R, Efrati S, Ashery U. Hyperbaric oxygen therapy as a new treatment approach for Alzheimer's disease. Neural Regen Res. 2018 May;13(5):817-818. PMID: https://www.ncbi.nlm.nih.gov/pubmed/29863011 Free PMC article. No abstract available.
Shapira R, Gdalyahu A, Gottfried I et al Hyperbaric oxygen therapy alleviates vascular dysfunction and amyloid burden in an Alzheimer's disease mouse model and in elderly patients. Aging (Albany NY). 2021 Sep 9;13(17):20935-20961. Epub 2021 Sep 9. PMID: https://www.ncbi.nlm.nih.gov/pubmed/34499614 Free PMC article.