liver transplantation

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Introduction

Cadaveric & living donor liver* transplants.

* Transplant of left lateral segment, left lobe or right lobe of the liver obtained from a living donor (> 90% of donors are relatives)

Indications

* Early referral

# alcoholic cirrhosis has surpassed hepatitis C infection as most common indication for liver transplantation[8]

Contraindications

Advanced age is a relative contraindication[1]

Laboratory

Complications

Management

More general terms

Additional terms

References

  1. 1.0 1.1 1.2 1.3 1.4 Medical Knowledge Self Assessment Program (MKSAP) 11, 15, 16, 17, 18. American College of Physicians, Philadelphia 1998, 2009, 2012, 2015, 2018.
  2. Journal Watch 21(20):62, 2001 Miller CM et al, One hundred nine living donor liver transplants in adults and children: a single-center experience. Ann Surg 234:301, 2001 PMID: https://www.ncbi.nlm.nih.gov/pubmed/11524583
  3. Engels EA et al. Spectrum of cancer risk among US solid organ transplant recipients. JAMA 2011 Nov 2; 306:1891. PMID: https://www.ncbi.nlm.nih.gov/pubmed/22045767
  4. Ahmed A, Keeffe EB. Current indications and contraindications for liver transplantation. Clin Liver Dis. 2007 May;11(2):227-47. PMID: https://www.ncbi.nlm.nih.gov/pubmed/17606204
  5. Moini M, Mistry P, Schilsky ML. Liver transplantation for inherited metabolic disorders of the liver. Curr Opin Organ Transplant. 2010 Jun;15(3):269-76 PMID: https://www.ncbi.nlm.nih.gov/pubmed/20489626
  6. 6.0 6.1 Dutkowski P et al. Challenges to liver transplantation and strategies to improve outcomes. Gastroenterology 2015 Feb; 148:307 PMID: https://www.ncbi.nlm.nih.gov/pubmed/25224524
  7. Sharma S, Gurakar A, Jabbour N. Avoiding pitfalls: what an endoscopist should know in liver transplantation--part 1. Dig Dis Sci. 2008 Jul;53(7):1757-73. Epub 2007 Nov 9. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/17990105
    Sharma S, Gurakar A, Camci C, Jabbour N. Avoiding pitfalls: what an endoscopist should know in liver transplantation--part II. Dig Dis Sci. 2009 Jul;54(7):1386-402. Epub 2008 Dec 17. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/19085103
  8. 8.0 8.1 Cholankeril G, Ahmed A. Alcoholic liver disease replaces hepatitis C virus infection as the leading indication for liver transplantation in the United States. Clin Gastroenterol Hepatol 2017 Nov 30; <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/29199144 <Internet> http://linkinghub.elsevier.com/retrieve/pii/S1542356517314180
  9. 9.0 9.1 European Association for the Study of the Liver EASL Clinical Practice Guidelines: Management of alcohol- related liver disease. J Hepatol. 2018 Apr 5. pii: S0168-8278(18)30214-9 PMID: https://www.ncbi.nlm.nih.gov/pubmed/29628280 https://www.journal-of-hepatology.eu/article/S0168-8278(18)30214-9/fulltext
  10. Krowka MJ, Fallon MB, Kawut SM et al International Liver Transplant Society Practice Guidelines: Diagnosis and Management of Hepatopulmonary Syndrome and Portopulmonary Hypertension. Transplantation. 2016 Jul;100(7):1440-52. PMID: https://www.ncbi.nlm.nih.gov/pubmed/27326810
  11. National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Liver Transplantat https://www.niddk.nih.gov/health-information/liver-disease/liver-transplant

Patient information

liver transplantation patient information