assisted reproduction technology (ART)

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Indications

Methods

Complications

* Most children born via ART are entirely normal

* ref[4] reports lower risks

* ~60% of women have a live birth[5]

* with autologous oocytes, birth rates decline with increasing maternal age[5]

* with donor oocytes, birth rates are > 60%, regardless of patient age[5]

* best outcomes occur when fewer embryos are transferred[6]

Notes

More general terms

More specific terms

Additional terms

References

  1. Journal Watch 22(8):66, 2002 Lynch A etal, Obstet Gynecol 99:445, 2002 Hansen M et al N Engl J Med 346:725, 2002 Schieve LA et al, N Engl J Med 346:731, 2002 http://content.nejm.org/cgi/content/abstract/346/10/731 Sromberg B et al, Lancet 359:461, 2002
  2. 2.0 2.1 2.2 2.3 2.4 2.5 Shevell T, Malone FD, Vidaver J, Porter TF, Luthy DA, Comstock CH, Hankins GD, Eddleman K, Dolan S, Dugoff L, Craigo S, Timor IE, Carr SR, Wolfe HM, Bianchi DW, D'Alton ME. Assisted Reproductive Technology and Pregnancy Outcome. Obstet Gynecol. 2005 Nov;106(5):1039-1045. PMID: https://www.ncbi.nlm.nih.gov/pubmed/16260523
  3. Sutcliffe AG et al, Assisted reproductive therapies and imprinting disorders - A preliminary British survey Hum Reprod 2006; 21:1009 PMID: https://www.ncbi.nlm.nih.gov/pubmed/16361294
  4. 4.0 4.1 Davies MJ et al Reproductive Technologies and the Risk of Birth Defects N Engl J Med May 5, 2012 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/22559061 <Internet> http://www.nejm.org/doi/full/10.1056/NEJMoa1008095
  5. 5.0 5.1 5.2 5.3 Luke B et al Cumulative Birth Rates with Linked Assisted Reproductive Technology Cycles N Engl J Med 2012; 366:2483-2491 Not yet indexed in PubMmed http://www.nejm.org/doi/full/10.1056/NEJMoa1110238
  6. 6.0 6.1 Hansen M et al. Assisted reproductive technology and major birth defects in Western Australia. Obstet Gynecol 2012 Oct; 120:852. PMID: https://www.ncbi.nlm.nih.gov/pubmed/22996103
    Joshi N et al. Trends and correlates of good perinatal outcomes in assisted reproductive technology. Obstet Gynecol 2012 Oct; 120:843. PMID: https://www.ncbi.nlm.nih.gov/pubmed/22996102
  7. 7.0 7.1 Williams CL et al. Cancer risk among children born after assisted conception. N Engl J Med 2013 Nov 7; 369:1819 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/24195549 <Internet> http://www.nejm.org/doi/full/10.1056/NEJMoa1301675
  8. 8.0 8.1 8.2 Stenbek DS et al. Mental distress and personality in women undergoing GnRH agonist versus GnRH antagonist protocols for assisted reproductive technology. Hum Reprod 2015 Jan; 30:103 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/25398970 <Internet> http://humrep.oxfordjournals.org/content/30/1/103
  9. 9.0 9.1 Chiu YH, Williams PL, Gillman MW et al Association Between Pesticide Residue Intake From Consumption of Fruits and Vegetables and Pregnancy Outcomes Among Women Undergoing Infertility Treatment With Assisted Reproductive Technology. JAMA Intern Med. Published online October 30, 2017 PMID: https://www.ncbi.nlm.nih.gov/pubmed/29084307 https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2659557
    Landrigan PJ. Pesticides and Human Reproduction. JAMA Intern Med. Published online October 30, 2017 PMID: https://www.ncbi.nlm.nih.gov/pubmed/29084335 https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2659554