3-donor embryo
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Clinical significance
- mitochondria from a 3rd party donor replace defective mitochondria in the oocyte cytoplasm during in vitro fertilization
- spermatocytes from the father do not donate mitochondria during reproduction
- all mitchondria in offspring are derived from mother
Procedure
- assisted reporduction technology consistng of a mother's oocyte, a father's spermatocytes & mitochondia from a 3rd party donor
Notes
- critics fear advent of 'designer babies'
More general terms
References
- ↑ Physician's First Watch, Feb 27, 2014 David G. Fairchild, MD, MPH, Editor-in-Chief Massachusetts Medical Society http://www.jwatch.org
FDA Avisory Committee. Feb 24-25, 2014 2014 Meeting Materials, Cellular, Tissue and Gene Therapies Advisory Committee. http://www.fda.gov/AdvisoryCommittees/CommitteesMeetingMaterials/BloodVaccinesandOtherBiologics/CellularTissueandGeneTherapiesAdvisoryCommittee/ucm380047.htm