aneuploidy

Introduction

Cells having a number of chromosomes different from the haploid, diploid or integer multiple of the diploid chromsome number. In humans, other than 23X, 23Y, 46XX, 46XY, 92XXXX, 92XXYY (etc).

Clinical significance

• aneuploidy may be prognostic marker for range of different cancers
• tumor aneuploidy correlates with markers of immune evasion & with reduced response to immunotherapy

More general terms

• chromosomal aberration

More specific terms

• chromosome 12 aneuploidy
• chromosome 13 aneuploidy
• chromosome 13+18+21+X+Y aneuploidy
• chromosome 15+16+22 aneuploidy
• chromosome 18 aneuploidy
• chromosome 3+7+17 aneuploidy & chromosome 9p21 deletion
• chromosome 6p25, 6q23, 11q, 8q24 & 9p21 aneuploidy
• chromosome X & Y aneuploidy
• fetal aneuploidy test panel
• fetal chromosomal aneuploid genomic sequencing
• fetal chromosome 13+18+21+Y aneuploidy
• trisomy

Component of

• aneuploidy & chromosomal microdeletions