tracheitis
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Introduction
Inflammation of the mucous membrane of the trachea.
Etiology
- bacterial infection
- viral infection
- influenza
- respiratory syntytial virus (RSV)
- parainfluenza
- many cases follow measles
- relapsing polychondritis
- Down's syndrome may be predisposing factor
Epidemiology
- uncommon
- most < 3 years of age
- 75% of cases in winter
Clinical manifestations
- croupy of brassy cough
- inspiratory stridor
- wheezing is unusual
- fever (often > 102 F)
- thick, purulent secretions
- poorly mobilized
- may become inspissated
Laboratory
- complete blood count (CBC) (leukocytosis, left shift)
- gram stain & culture of tracheal secretions
- blood cultures are generally negative
Diagnostic procedures
Radiology
- lateral X-ray of neck (normal epiglottis)
Complications
- outcome may be fatal
Differential diagnosis
- viral croup
- epiglottitis
- diphtheria
- herpes simplex (necrotizing)
- cytomegalovirus (CMV) in immunosuppressed patients
- invasive Aspergillosis in immunosuppressed patients
Management
- airway maintenance
- suction
- endotracheal intubation as needed
- humidification of inspired gas
- antibiotic therapy
- IV administration for 5-6 days
- oral therapy continued for total duration of 2 weeks
- levofloxacin or 3rd generation cephalosporin