pharmaceutical extension of longevity

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[1][2][3][4][5][6][7][8]

Management

* factors in the systemic environment of the old animals inhibit muscle repair (see myogenic satellite cell)

More general terms

References

  1. ↑ 1.0 1.1 Ma Y, Liu Y, Han F 3r al Growth differentiation factor 11: a "rejuvenation factor" involved in regulation of age-related diseases? Aging (Albany NY). 2021 Apr 22;13(8):12258-12272. PMID: https://www.ncbi.nlm.nih.gov/pubmed/33886503 PMCID: PMC8109099 Free PMC article. Review.
    Patel VK, Demontis F. GDF11/myostatin and aging. Aging (Albany NY). 2014 May;6(5):351-2. PMID: https://www.ncbi.nlm.nih.gov/pubmed/24902527 PMCID: PMC4069261 Free PMC article.
    Bagheri R, Moghadam BH, Church DD et al The effects of concurrent training order on body composition and serum concentrations of follistatin, myostatin and GDF11 in sarcopenic elderly men. Exp Gerontol. 2020 May;133:110869. PMID: https://www.ncbi.nlm.nih.gov/pubmed/32035222 Clinical Trial.
  2. ↑ 2.0 2.1 Widjaja AA, Shekeran SG, Adami E et l A Neutralizing IL-11 Antibody Improves Renal Function and Increases Lifespan in a Mouse Model of Alport Syndrome. J Am Soc Nephrol. 2022 Apr;33(4):718-730. PMID: https://www.ncbi.nlm.nih.gov/pubmed/35140116 Free PMC article.
  3. ↑ 3.0 3.1 Kiprov D. Therapeutic plasma exchange (TPE) and blood products - Implications for longevity & disease. Transfus Apher Sci. 2021 Jun;60(3):103163. PMID: https://www.ncbi.nlm.nih.gov/pubmed/34074614 No abstract available.
  4. ↑ 4.0 4.1 Selvarani R, Mohammed S, Richardson A. Effect of rapamycin on aging and age-related diseases-past and future. Geroscience. 2021 Jun;43(3):1135-1158. PMID: https://www.ncbi.nlm.nih.gov/pubmed/33037985 Free PMC article. Review.
    Ehninger D, Neff F, Xie K. Longevity, aging and rapamycin. Cell Mol Life Sci. 2014 Nov;71(22):4325-46. PMID: https://www.ncbi.nlm.nih.gov/pubmed/25015322 Free PMC article. Review.
    Blagosklonny MV. Rapamycin for longevity: opinion article. Aging (Albany NY). 2019 Oct 4;11(19):8048-8067. PMID: https://www.ncbi.nlm.nih.gov/pubmed/31586989 PMCID: PMC6814615 Free PMC article.
  5. ↑ 5.0 5.1 Mohammed I, Hollenberg MD, Ding H, Triggle CR. A Critical Review of the Evidence That Metformin Is a Putative Anti-Aging Drug That Enhances Healthspan and Extends Lifespan. Front Endocrinol (Lausanne). 2021 Aug 5;12:718942. PMID: https://www.ncbi.nlm.nih.gov/pubmed/34421827 PMCID: PMC8374068 Free PMC article. Review.
    Glossmann HH, Lutz OMD. Metformin and Aging: A Review. Gerontology. 2019;65(6):581-590. PMID: https://www.ncbi.nlm.nih.gov/pubmed/31522175 Free article. Review.
    Soukas AA, Hao H, Wu L. Metformin as Anti-Aging Therapy: Is It for Everyone? Trends Endocrinol Metab. 2019 Oct;30(10):745-755. PMID: https://www.ncbi.nlm.nih.gov/pubmed/31405774 PMCID: PMC6779524 Free PMC article. Review.
    Kulkarni AS, Gubbi S, Barzilai N. Benefits of Metformin in Attenuating the Hallmarks of Aging. Cell Metab. 2020 Jul 7;32(1):15-30. PMID: https://www.ncbi.nlm.nih.gov/pubmed/32333835 PMCID: PMC7347426 Free PMC article. Review.
    Kozlov M The brain aged more slowly in monkeys given a cheap diabetes drug. Daily dose of the common medication metformin preserved cognition and delayed decline of some tissues. Nature. News. Sept 12, 2024 https://www.nature.com/articles/d41586-024-02938-w
    Yang Y, Lu X, Liu N et al Metformin decelerates aging clock in male monkeys. Cell. September 12, 2024 PMID: https://www.ncbi.nlm.nih.gov/pubmed/39270656 https://www.cell.com/cell/abstract/S0092-8674(24)00914-0
  6. ↑ 6.0 6.1 Venn-Watson S, Lumpkin R, Dennis EA. Efficacy of dietary odd-chain saturated fatty acid pentadecanoic acid parallels broad associated health benefits in humans: could it be essential? Sci Rep. 2020 May 18;10(1):8161. PMID: https://www.ncbi.nlm.nih.gov/pubmed/32424181 PMCID: PMC7235264 Free PMC article.
    Venn-Watson SK, Butterworth CN. Broader and safer clinically-relevant activities of pentadecanoic acid compared to omega-3: Evaluation of an emerging essential fatty acid across twelve primary human cell-based disease systems. PLoS One. 2022 May 26;17(5):e0268778. PMID: https://www.ncbi.nlm.nih.gov/pubmed/35617322 PMCID: PMC9135213 Free PMC article.
    Venn-Watson S, Schork NJ. Pentadecanoic Acid (C15:0), an Essential Fatty Acid, Shares Clinically Relevant Cell-Based Activities with Leading Longevity-Enhancing Compounds. Nutrients. 2023 Oct 30;15(21):4607. PMID: https://www.ncbi.nlm.nih.gov/pubmed/37960259 PMCID: PMC10649853 Free PMC article.
  7. ↑ Helper C, Bass J Supplements to treat prediabetes. Science. 2021 Jun 11;372(6547):1147-1148. PMID: https://www.ncbi.nlm.nih.gov/pubmed/34112679 PMCID: PMC10020896 Free PMC article. https://www.science.org/doi/10.1126/science.abj0764
  8. ↑ 8.0 8.1 Monaco K Hormone Therapy May Slow Biological Aging in Women, Study Suggests. But further investigations capable are warranted to confirm the findings, researcher says. MedPage Today. August 29, 2024 https://www.medpagetoday.com/obgyn/hrt/111721
    Liu Y, Li C Hormone Therapy and Biological Aging in Postmenopausal Women. JAMA Netw Open. 2024;7(8):e2430839. Aug 29 PMID: https://www.ncbi.nlm.nih.gov/pubmed/39207753 https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2822953
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