metanephrines in urine

Indications

• screening test of choice for pheochromocytoma

Reference interval

• see metanephrines in 24 hour urine

Increases

• catecholamine-secreting neurochromaffin tumors
  • pheochromocytoma
  • paraganglioma
  • neuroblastome
• pharmaceutical agents:
  • in vivo effects
    • nitroglycerin, phenothiazines
  • chemical interferences
    • vitamin B (high doses), erythromycin, hydralazine, levodopa, methenamine hippurate, methenamine mandelate, methyldopa, nicotinic acid, quinine, quinidine, salicylate, tetracyclines

Decreases

• pharmaceutical agents:
  • in vivo effects
    • MAO inhibitors

Interferences

• sympathomimetics
• tricyclic antidepressants
• labetalol

More general terms

• urine chemistry test

More specific terms

• metanephrines in 24 hour urine

Additional terms

• metanephrine
• pheochromocytoma; paroxysmal hypertension; adrenal medullary paraganglioma; chromoffinoma

Component of

• metanephrines/creatinine in urine