hydralazine (Apresoline)

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Introduction

Tradename: Apresoline.

Indications

Contraindications

Caution:

pregnancy category = c

safety in lactation = +

Dosage

Tabs: 10, 25 50, 100 mg.

Injection: 20 mg/mL (1 mL).

Pharmacokinetics

elimination via liver

elimination via kidney

1/2life = 2-5 hours

Adverse effects

Tolerance: may occur, but may be reduced by concomitant diuretic use

Drug interactions

Mechanism of action

More general terms

Component of

References

  1. The Pharmacological Basis of Therapeutics, 9th ed. Gilman et al, eds. Permagon Press/McGraw Hill, 1996
  2. Manual of Medical Therapeutics, 28th ed, Ewald & McKenzie (eds), Little, Brown & Co, Boston, 1995, pg 118.
  3. AHFS Drug Information, American Society of Health-System Pharmacists, Bethesda, 1998
  4. Kaiser Permanente Northern California Regional Drug Formulary, 1998
  5. Jump up to: 5.0 5.1 Drug Information & Medication Formulary, Veterans Affairs, Central California Health Care System, 1st ed., Ravnan et al eds, 1998
  6. Jump up to: 6.0 6.1 Mayo Internal Medicine Board Review, 1998-99, Prakash UBS (ed) Lippincott-Raven, Philadelphia, 1998, pg 476
  7. Jump up to: 7.0 7.1 7.2 Medical Knowledge Self Assessment Program (MKSAP) 19. American College of Physicians, Philadelphia 2021

Database