Sulfacetamide Ophthalmic (Sulamyd, Bleph-10, Sulf-10)
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Introduction
Tradenames: Sulamyd, Bleph-10, Sulf-10
Indications
- eye infection, eyelid disease
- topical treatment of conjunctivitis due to Escherichia coli, S aureus, S pneumoniae, Streptococcus viridans, H influenzae, Klebsiella, Enterococcus
- corneal ulcers
- adjunctive treatment with systemic sulfonamides for trachoma
Contraindications
Dosage
- 1 drop every 1-6 hours
- ointment BID-QID
- trachoma: 2 drops every 2 hours in combination with appropriate systemic therapy
Drops: 10%, 15%, 30%. ( 5 mL, 15 mL).
Antimicrobial activity
Adverse effects
- not common (1-10%)
- local burning, stinging, irritation
- uncommon (< 1%)
- headache, Stevens-Johnson syndrome, exfoliative dermatitis, toxic epidermal necrolysis, blurred vision, hypersensitivity reaction, browache
- drug adverse effects of sulfonamides
- drug adverse effects of diuretics
- drug adverse effects of carbonic anhydrase inhibitor(s)
- drug adverse effects of antihypertensive agents
Mechanism of action
- inhibition of bacterial folic acid synthesis
More general terms
References
- ↑ The Pharmacological Basis of Therapeutics, 9th ed. Gilman et al, eds. Permagon Press/McGraw Hill, 1996
- ↑ Drug Information & Medication Formulary, Veterans Affairs, Central California Health Care System, 1st ed., Ravnan et al eds, 1998
- ↑ Kaiser Permanente Northern California Regional Drug Formulary, 1998
- ↑ Jump up to: 4.0 4.1 4.2 Deprecated Reference
- ↑ MedlinePlus: Sulfacetamide Ophthalmic https://medlineplus.gov/druginfo/meds/a601114.html
- ↑ DailyMed: SULFACETAMIDE SODIUM - sulfacetamide sodium solution https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=92f53dc3-cedc-4963-911a-77c3431d4765&type=display