demyelinating disease
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Classification
- idiopathic inflammatory CNS demyelinating disorders are defined by their distribution, clinical symptoms, severity & tendency to relapse
Epidemiology
- multiple sclerosis is the most common CNS demyelinating disorder
Comparative biology
- miconazole & clobetasol promote remyelination in mouse demyelinating disease
- these 2 agents induced mouse oligodendrocyte-progenitor stem cells to turn into myelin-producing oligodendrocytes[2]
More general terms
More specific terms
- acute hemorrhagic leukoencephalopathy
- autosomal dominant adult-onset leukodystrophy (autosomal dominant Pelizaeus-Merzbacher disease)
- central pontine myelinolysis (osmotic demyelination syndrome)
- encephalomyelitis
- inflammatory demyelinating polyneuropathy
- Marchiafava-Bignami disease
- multiple sclerosis (MS)
- Pelizaeus-Merzbacher disease
- progressive multifocal leukoencephalopathy (PML)
- transverse myelitis
Additional terms
References
- ↑ Medical Knowledge Self Assessment Program (MKSAP) 15, American College of Physicians, Philadelphia 2009
- ↑ 2.0 2.1 Najm FJ et al. Drug-based modulation of endogenous stem cells promotes functional remyelination in vivo. Nature 2015 Jun 11; 522:216. PMID: https://www.ncbi.nlm.nih.gov/pubmed/25896324