acute hemorrhagic leukoencephalopathy

Etiology

• idiopathic

Epidemiology

• much less common than acute disseminated encephalomyelitis

Pathology

• hyperacute form of acute disseminated encephalomyelitis
• perivenular demyelination
• diffuse hemorrhagic necrosis of the central nervous system

Complications

• death is the usual outcome

Management

• not well established
• combination of immunosuppression &plasma exchange has been proposed

More general terms

• leukoencephalopathy
• autoimmune disease
• demyelinating disease
• hemorrhagic stroke