leukoencephalopathy

Etiology

• radiation
• chemotherapy
• CADASIL
• progressive multifocal leukoencephalopathy (PML)

Pathology

• white matter changes characterized by:
  • diffuse reactive astrocytosis
  • multiple foci of necrosis
  • inflammation

More general terms

• encephalopathy

More specific terms

• acute hemorrhagic leukoencephalopathy
• Binswanger's disease (subcortical atherosclerotic encephalopathy)
• leukoencephalopathy with brainstem & spinal cord involvement & lactate elevation (LBSL)
• megalencephalic leukoencephalopathy with subcortical cysts
• progressive multifocal leukoencephalopathy (PML)
• reversible posterior leukoencephalopathy syndrome (RPLS)

Additional terms

• CADASIL (cerebral autosomal dominant arteriopathy with subcortical infarcts & leukoencephalopathy)