methamphetamine

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Pharmacokinetics

elimination via liver

Adverse effects

Drug interactions

  • any pharmaceutical agent that inhibits cyt P450 2D6 may increase methamphetamine levels

Laboratory

Mechanism of action

Notes

More general terms

Additional terms

References

  1. Clinical Guide to Laboratory Tests, 3rd ed. Teitz ed., W.B. Saunders, 1995
  2. Prescriber's Letter 13(3): 2006 Cytochrome P450 drug interactions Detail-Document#: http://prescribersletter.com/(5bhgn1a4ni4cyp2tvybwfh55)/pl/ArticleDD.aspx?li=1&st=1&cs=&s=PRL&pt=3&fpt=25&dd=220233&pb=PRL (subscription needed) http://www.prescribersletter.com
  3. 3.0 3.1 3.2 Lineberry TW & Bostwick JM Methamphetamine abuse: a perfect storm of complications Mayo Clin Proc 2006; 81:77
  4. 4.0 4.1 Briere FN et al Prospective associations between meth/amphetamine (speed) and MDMA (ecstasy) use and depressive symptoms in secondary school students J Epidemiol Community Health doi:10.1136/jech-2011-200706 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/22516739 <Internet> http://jech.bmj.com/content/early/2012/04/12/jech-2011-200706.abstract
  5. 5.0 5.1 Chang L, Oishi K, Skranes J et al. Sex-specific alterations of white matter developmental trajectories in infants with prenatal exposure to methamphetamine and tobacco. JAMA Psychiatry 2016 Nov 9; PMID: https://www.ncbi.nlm.nih.gov/pubmed/27829078
    Roos A, Donald KA. Refining the understanding of the effects of prenatal methamphetamine and tobacco exposure on the developing brain. JAMA Psychiatry 2016 Nov 9 PMID: https://www.ncbi.nlm.nih.gov/pubmed/27829080
  6. 6.0 6.1 Schurer S, Klingel K, Sandri M et al Clinical Characteristics, Histopathological Features, and Clinical Outcome of Methamphetamine-Associated Cardiomyopathy. JACC: Heart Failure. Volume 5, Issue 6, June 2017 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/28571597 <Internet> http://www.heartfailure.onlinejacc.org/content/5/6/435
    Ahmad T, Schroder JN, Januzzi JL Jr. Breaking Bad. The Heartbreak of Drug Abuse. JACC: Heart Failure. Volume 5, Issue 6, June 2017 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/28571598 <Internet> http://www.heartfailure.onlinejacc.org/content/5/6/446
  7. 7.0 7.1 Birath JB, Briones M, Amaya S et al. Ibudilast may improve attention during early abstinence from methamphetamine. Drug Alcohol Depend 2017 Jun 23; 178:386. PMID: https://www.ncbi.nlm.nih.gov/pubmed/2870476
  8. 8.0 8.1 Manja V, Nrusimha A, Gao Y et al Methamphetamine-associated heart failure: a systematic review of observational studies. Heart. 2022 Dec 1;heartjnl-2022-321610. PMID: https://www.ncbi.nlm.nih.gov/pubmed/36456204 https://heart.bmj.com/content/early/2022/11/15/heartjnl-2022-321610
  9. 9.0 9.1 Medical Knowledge Self Assessment Program (MKSAP) 19 Board Basics. An Enhancement to MKSAP19. American College of Physicians, Philadelphia 2022

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