ketotifen (Zaditor, Zaditen, Alaway, Claritin Eye, Zyrtec Itchy Eye Drops)

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Introduction

Tradenames: Zaditor, Zaditen, Alaway, Claritin Eye, Zyrtec Itchy Eye Drops

Indications

Dosage

1 drop in affected eye(s) BID Ophthalmic solution: 0.025%, 1 mL, 5 mL 0.345 mg ketotifen fumarate (0.25 mg ketotifen)/mL

Contains: glycerol, benzalkonium chloride 0.01% pH: 4.4-5.8, osmolality 210-300 mOsm/kg

Storage

4-25 C

Pharmacokinetics

  • systemic concentrations below detection (20 pg/mL) after topical administration

Adverse effects

Toxicity:

  • no serious toxicity after ingestion of 20 mg of ketotifen fumarate (1.725 mg/5 mL bottle)

Mechanism of action

More general terms

References

  1. Novartis
  2. Prescriber's Letter 14(1): 2007 Ophthalmic Medications for Allergic Conjunctivitis Detail-Document#: http://prescribersletter.com/(5bhgn1a4ni4cyp2tvybwfh55)/pl/ArticleDD.aspx?li=1&st=1&cs=&s=PRL&pt=3&fpt=25&dd=230106&pb=PRL (subscription needed) http://www.prescribersletter.com
  3. Prescriber's Letter 16(10): 2009 CHART: OTC Brand Name Extensions COMMENTARY: Brand Name Extensions, Reformulations, and Labeling Revisions of OTC Products Detail-Document#: http://prescribersletter.com/(5bhgn1a4ni4cyp2tvybwfh55)/pl/ArticleDD.aspx?li=1&st=1&cs=&s=PRL&pt=3&fpt=25&dd=251012&pb=PRL (subscription needed) http://www.prescribersletter.com

Database