ketotifen (Zaditor, Zaditen, Alaway, Claritin Eye, Zyrtec Itchy Eye Drops)
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Introduction
Tradenames: Zaditor, Zaditen, Alaway, Claritin Eye, Zyrtec Itchy Eye Drops
Indications
Dosage
1 drop in affected eye(s) BID Ophthalmic solution: 0.025%, 1 mL, 5 mL 0.345 mg ketotifen fumarate (0.25 mg ketotifen)/mL
Contains: glycerol, benzalkonium chloride 0.01% pH: 4.4-5.8, osmolality 210-300 mOsm/kg
Storage
4-25 C
Pharmacokinetics
Adverse effects
- ocular:
- non-ocular
- flu-like syndrome, pharyngitis
Toxicity:
Mechanism of action
- non-competitive histamine H1 receptor antagonist
- mast cell stabilizer
- decreased chemotaxis & activation of eosinophils
More general terms
References
- ↑ Novartis
- ↑ Prescriber's Letter 14(1): 2007 Ophthalmic Medications for Allergic Conjunctivitis Detail-Document#: http://prescribersletter.com/(5bhgn1a4ni4cyp2tvybwfh55)/pl/ArticleDD.aspx?li=1&st=1&cs=&s=PRL&pt=3&fpt=25&dd=230106&pb=PRL (subscription needed) http://www.prescribersletter.com
- ↑ Prescriber's Letter 16(10): 2009 CHART: OTC Brand Name Extensions COMMENTARY: Brand Name Extensions, Reformulations, and Labeling Revisions of OTC Products Detail-Document#: http://prescribersletter.com/(5bhgn1a4ni4cyp2tvybwfh55)/pl/ArticleDD.aspx?li=1&st=1&cs=&s=PRL&pt=3&fpt=25&dd=251012&pb=PRL (subscription needed) http://www.prescribersletter.com