malignant fibrous histiocytoma (MFH, angiomatoid fibrous histiocytoma)

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Introduction

most commonly diagnosed sarcoma of extremities.

Epidemiology

  • older adults
  • peak incidence 7th decade
  • angiomatoid variant occurs in children & adolescents

Microscopic pathology

(subtypes)

Genetics

Clinical manifestations

Management

More general terms

References

  1. 1.0 1.1 National Cancer Institute - Osteosarcoma/Bone Fibrous Histiocytoma Treatment http://www.nci.nih.gov/cancertopics/pdq/treatment/osteosarcoma/healthprofessional
  2. DeVita et al. Cancer, Principles & Practice of Oncology. Lippincott, Williams & Wilkins 6th ed. 2001
  3. Sakamoto A, Oda Y, Adachi T, Saito T, Tamiya S, Iwamoto Y, Tsuneyoshi M. Beta-catenin accumulation and gene mutation in exon 3 in dedifferentiated liposarcoma and malignant fibrous histiocytoma. Arch Pathol Lab Med. 2002 Sep;126(9):1071-8. PMID: https://www.ncbi.nlm.nih.gov/pubmed/12204056

Patient information

malignant fibrous histiocytoma patient information

Database