core histone macro-H2A.1; histone macroH2A1; medulloblastoma antigen MU-MB-50.205 (H2AFY, MACROH2A1, mH2A1, H2A.y, H2A/y)

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Function

Structure

Compartment

Alternative splicing

named isoforms=2 Note=Specifically binds ADP-ribose and O-acetyl-ADP-ribose Important residues for binding are Asp-203, Gly-224, Gly-314 and Phe-348

Expression

ubiquitous

Pathology

  • number of individuals with antibodies against H2AFY is 2-fold higher in pediatric patients with cancer compared to healthy controls

More general terms

References

Database