forkhead box protein O1A; forkhead in rhabdomyosarcoma; FKHR protein (FOXO1A)

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Function

Structure

contains 1 fork-head DNA-binding domain

Compartment

Expression

ubiquitous

Pathology

Polymorphism

More general terms

References

  1. OMIM https://mirror.omim.org/entry/136533
  2. Entrez Gene http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=2308
  3. UniProt http://www.uniprot.org/uniprot/Q12778.html
  4. 4.0 4.1 Nakae J, Cao Y, Daitoku H, Fukamizu A, Ogawa W, Yano Y, Hayashi Y. The LXXLL motif of murine forkhead transcription factor FoxO1 mediates Sirt1-dependent transcriptional activity. J Clin Invest. 2006 Sep;116(9):2473-83. Epub 2006 Aug 17. PMID: https://www.ncbi.nlm.nih.gov/pubmed/16917544
  5. 5.0 5.1 Li Y et al Genetic association of FOXO1A and FOXO3A with longevity trait in Han Chinese populations. Hum Mol Genet. 2009 Dec 15;18(24):4897-904. PMID: https://www.ncbi.nlm.nih.gov/pubmed/19793722

Database