chromosomal translocation t(2;13)(q35;q14)

Introduction

• chromosomal translocation t(2;13)(q35;q14) involving FOXO1A with PAX3 & t(1;13)(p36;q14) with PAX7 are a cause of alveolar rhabdomyosarcoma
• resulting protein is a transcriptional activator

More general terms

• chromosomal translocation

Additional terms

• forkhead in rhabdomyosarcoma (FKHR) gene
• PAX3, WS1, HUP2 or CDHS gene