AP-2 complex subunit alpha-2; adapter-related protein complex 2 alpha-2 subunit; adaptor protein complex AP-2 subunit alpha-2; alpha2-adaptin; plasma membrane adaptor HA2/AP2 adaptin alpha C subunit; alpha-adaptin C; clathrin assembly protein complex 2 alpha-C large chain; 100 kD coated vesicle protein C; Huntingtin-interacting protein J; Huntingtin yeast partner J (AP2A2, ADTAB, CLAPA, HYPJ, KIAA0899)
Jump to navigation
Jump to search
Function
- subunit of clathrin-associated adaptor protein complex 2 (HA2-AP2 adaptor complex)
- binds polyphosphoinositides (putative)
- binds EPN1, EPS15, AMPH, SNAP91 & BIN1 (putative)
- component of a complex composed at least of ACTB, AP2M1, AP2A1, AP2A2, MEGF10 & VIM
Structure
belongs to the adaptor complexes large subunit family
Compartment
- cell membrane, coated pit
- peripheral membrane, cytoplasmic side
- component of the coat surrounding the cytoplasmic face of coated vesicles in the plasma membrane