FK506 binding protein (FKBP)

Function

• FK506- & rapamycin-binding proteins (FKBPs) constitute a family of receptors for the two immunosuppressants which inhibit T-cell proliferation by arresting two distinct cytoplasmic signal transmission pathways
• PPIases accelerate the folding of proteins

More general terms

• immunophilins (includes cyclophilins & FK506 binding proteins)

More specific terms

• FK506-binding protein 10 (65 kD FK506-binding protein, immunophilin FKBP65, FKBP10)
• FK506-binding protein 11 (19 kD FK506-binding protein, FKBP11, FKBP19)
• FK506-binding protein 14 (22 kD FK506-binding protein, FKBP14, FKBP22)
• FK506-binding protein 1A (12 kD FK506-binding protein, immunophilin FKBP12, FKBP1A)
• FK506-binding protein 1B (12.6 kD FK506-binding protein, immunophilin FKBP12.6, FKBP1B)
• FK506-binding protein 2 (13 kD FK506-binding protein, FKBP2)
• FK506-binding protein 3, 25 kD FK506-binding protein or rapamycin-selective 25 kD immunophilin
• FK506-binding protein 4 (52 kD FK506 binding protein, hsp-binding immunophilin, FKBP59, FKBP4)
• FK506-binding protein 5 (51 kD FK506-binding protein, 54 kD progesterone receptor-associated immunophilin, FKBP54, FF1 antigen, HSP90-binding immunophilin, androgen-regulated protein 6, FKBP5)
• FK506-binding protein 6 (36 kD FK506-binding protein, immunophilin FKBP36, FKBP6)
• FK506-binding protein 7
• FK506-binding protein 8 (38 kD FK506-binding protein homolog, FKBP8, FKBP38, FKBPR38)
• FK506-binding protein 9 (FKBP9 FKBP60 FKBP63)
• FK506-binding protein 9-like protein (FKBP9L)

Additional terms

• glomulin (GLMN FK506-binding protein-associated protein, 48 kD)