sentinel lymph node procedure
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Indications
- breast cancer
- cancer of the vulva
- cervical cancer
- prostate cancer
- bladder cancer
- thyroid cancer
- head & neck cancer
- colon cancer
- rectal cancer
- gastric cancer
- non-small-cell lung cancer
- Merkel cell cancer
- cutaneous melanoma (intermediate-thickness)
Laboratory
Procedure
- injection of blue dye or technetium-99m with gamma-probe localization allows a minimally invasive technique for detecting melanoma (or other cancer) metastases to local lymph nodes
- the nodes are then resected (intact) & checked for cancer
- radiation therapy may be directed at the site of the surgery & to nearby lymph nodes to destroy any remaining cancer cells
More general terms
Additional terms
References
- ↑ Color Atlas & Synopsis of Clinical Dermatology, Common & Serious Diseases, 3rd ed, Fitzpatrick et al, McGraw Hill, NY, 1997, pg 978
- ↑ 2.0 2.1 Civantos FJ et al. Sentinel lymph node biopsy accurately stages the regional lymph nodes for T1-T2 oral squamous cell carcinomas: Results of a prospective multi-institutional trial. J Clin Oncol 2010 Mar 10; 28:1395. PMID: https://www.ncbi.nlm.nih.gov/pubmed/20142602
- ↑ Wong SL, Faries MB, Kennedy EB, et al. Sentinel Lymph Node Biopsy and Management of Regional Lymph Nodes in Melanoma: American Society of Clinical Oncology and Society of Surgical Oncology Clinical Practice Guideline Update. Ann Surg Oncol. 2018 Feb;25(2):356-377. PMID: https://www.ncbi.nlm.nih.gov/pubmed/29236202 https://www.ncbi.nlm.nih.gov/pubmed/29236202
- ↑ Sentinel Lymph Node Biopsy: Questions and Answers National Cancer Institute http://www.cancer.gov/cancertopics/factsheet/therapy/sentinel-node-biopsy