brain aging

Introduction

A term used in the literature inconjunction with grey matter atrophy, MRI white matter hyperintensity & cardiovascular health.

Management

• a more favorable cardiovascular health profile* is associated with slower white matter hyperintensity progression
• genetic risk* is associated with faster white matter hyperintensity progression, except if favorable global or behavioral cardiovascular health profile
• genetic risk* is associated with faster grey matter atrophy

* cardiovascular health profile determined by

• 4 behavioral factors: 0 smoking, physical activity, dietary habits, body-mass index
• 3 biological factors:
  • total serum cholesterol, blood pressure, fasting plasma glucose from Life's Simple 7

* genetic risk scores determined by the presence of risk alleles for

• hypertension, diabetes, or dyslipidemia

More general terms

• aging

Additional terms

• MRI cerebral white matter lesion (white matter hyperintensity)