Amcinonide Topical

Introduction

Tradename: Cyclocort.

Indications

• short term relief of inflammation & pruritus (dermatitis)
  • seborrheic dermatitis
  • atopic dermatitis
  • contact dermatitis
• allergies
• cutaneous T-cell lymphoma
• discoid lupus
• granuloma annulare
• psoriasis
• lichen simplex chronicus

Dosage

• Topical: 0.1% cream/ointment/lotion BID/TID, high potency (0.1%).

Cream: 15 & 60 g.

Lotion: 10 & 60 mL.

Ointment: 15 & 60 g.

Adverse effects

• not common (1-10%)
  • itching, maceration of skin, skin atrophy, erythema, dryness, papular rashes, burning, irritation
• uncommon (< 1%)
  • hypertrichosis, acneiform eruptions, hypopigmentation, perioral dermatitis, striae, miliaria

• drug adverse effects of glucocorticoids
• drug adverse effects of topical glucocorticoids
• drug adverse effects of immunosuppressive agents

Mechanism of action

• anti-inflammatory; topical glucocorticoid class 3

More general terms

• amcinonide
• topical glucocorticoid (topical steroid)