Fluocinonide Topical (Lidex)

Indications

• relief of inflammatory dermatoses (dermatitis)
  • allergic dermatitis
    • atopic dermatitis, contact dermatitis
  • seborrheic dermatitis
  • dandruff
  • discoid lupus
  • granuloma annulare
  • psoriasis
  • pruritus, anal pruritus
  • lichen simplex chronicus
• alleriges
• cutaneous T-cell lymphoma

Dosage

Topical:

• apply BID/QID

cream/ointment/solution/gel 0.05%.

cream/ointment/gel(15 g, 30 g, 60 g)

solution (20 mL, 60 mL)

High potency (0.05%).

Adverse effects

• uncommon (< 1%)
  • burning, itching, skin irritation, dryness, folliculitis, hypertrichosis, acne, hypopigmentation, perioral dermatitis, allergic contact dermatitis, skin maceration, secondary infection, skin atrophy, striae, miliaria, intracranial hypertension, hypothalamic-pituitary-adrenal axis suppression, Cushing's syndrome, growth retardation

• drug adverse effects of glucocorticoids
• drug adverse effects of topical glucocorticoids
• drug adverse effects of immunosuppressive agents

Mechanism of action

• anti-inflammatory high-potency topical glucocorticoid (class 2)

More general terms

• fluocinonide (Fluonex)
• topical glucocorticoid (topical steroid)