Fluocinolone Topical (Synalar, Synemol, Fluonid, Derma-Smoothe/FS, Synandrone)
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Indications
- relief of inflammatory dermatoses (dermatitis)
- alleriges
- cutaneous T-cell lymphoma[4]
Dosage
Cream: 0.01%, 0.025%, 0.2%.
Ointment: 0.025%.
Solution: 0.01%.
Shampoo: 0.01%. Oil: (Derma-Smoothe/FS) 0.01% (120 mL)
Low potency (0.01%).
Occlusive dressings may be used for resistant or severe dermatoses
Adverse effects
- uncommon (< 1%)
- burning, itching, skin irritation, dryness, folliculitis, hypertrichosis, acne, hypopigmentation, perioral dermatitis, allergic contact dermatitis, skin maceration, secondary infection, skin atrophy, striae, miliaria, intracranial hypertension, hypothalamic-pituitary-adrenal axis suppression, Cushing's syndrome, growth retardation
- drug adverse effects of glucocorticoids
- drug adverse effects of topical glucocorticoids
- drug adverse effects of immunosuppressive agents
Mechanism of action
- anti-inflammatory; topical glucocorticoid class 4, class 5
More general terms
References
- ↑ The Pharmacological Basis of Therapeutics, 9th ed. Gilman et al, eds. Permagon Press/McGraw Hill, 1996
- ↑ Drug Information & Medication Formulary, Veterans Affairs, Central California Health Care System, 1st ed., Ravnan et al eds, 1998
- ↑ Kaiser Permanente Northern California Regional Drug Formulary, 1998
- ↑ 4.0 4.1 4.2 Deprecated Reference
- ↑ Medical Knowledge Self Assessment Program (MKSAP) 17, American College of Physicians, Philadelphia 2015
- ↑ Department of Veterans Affairs, VA National Formulary