caffeine/ergotamine (Cafergot, Ercaf, Wigraine)

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Indications

prevention or treatment of vascular headaches

Contraindications

pregnancy-category X

safety in lactation -

Dosage

1 mg ergotamine + 100 mg caffeine.

  • 2 tabs PO at onset, then 1 every 30 min
  • up to 6 tabs/24 hours

Suppositories: (2 mg ergotamine + 100 mg caffeine).

  • up to 2/attack.

Pharmacokinetics

Adverse effects

Drug interactions

Mechanism of action

More general terms

Components

References

  1. The Pharmacological Basis of Therapeutics, 9th ed. Gilman et al, eds. Permagon Press/McGraw Hill, 1996
  2. Drug Information & Medication Formulary, Veterans Affairs, Central California Health Care System, 1st ed., Ravnan et al eds, 1998
  3. Kaiser Permanente Northern California Regional Drug Formulary, 1998

Database