analgesic rebound headache (transformed headache)
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Etiology
- daily use of analgesics
- drug tolerance
History
- severity of dependence scale may be useful screening tool[3]
Clinical manifestations
- often occur in the morning or upon awakening
- generally diffuse
- prophylactic medications ineffective
Management
- patient education
- avoid butalbital & opioids as these agents are associated with increased risk of analgesic rebound headaache[4]
- prophylactic therapy:
- amitriptyline (Elavil) 10-75 mg PO QHS
- desipramine (Norpramin) 1-50 mg PO QHS
- valproic acid
- allow analgesic use to continue for 3-4 weeks while patient is stabilizing on prophylactic therapy
- taper analgesics over 1 week
More general terms
References
- ↑ Kaiser Permanente, Videoconference, 9/9/99, Fresno CA
- ↑ Zeeberg P et al, Probable medication-overuse headache: The effect of a 2-month drug-free period. Neurology 2006, 66:1894 PMID: https://www.ncbi.nlm.nih.gov/pubmed/16707727
- ↑ Jump up to: 3.0 3.1 Grande RB et al The Severity of Dependence Scale detects people with medication overuse: The Akershus study of chronic headache. J Neurol Neurosurg Psychiatry 2009 Jul; 80:784. PMID: https://www.ncbi.nlm.nih.gov/pubmed/19279030
Lucas C and Diener H-C. The dependence scale: An easy tool to detect chronic daily headache with mediation overuse? J Neurol Neurosurg Psychiatry 2009 Jul; 80:704. PMID: https://www.ncbi.nlm.nih.gov/pubmed/19531683 - ↑ Jump up to: 4.0 4.1 4.2 Medical Knowledge Self Assessment Program (MKSAP) 14, 17, 18, 19. American College of Physicians, Philadelphia 2006, 2015, 2018, 2021.
- ↑ Johnson JL, Hutchinson MR, Williams DB, Rolan P. Medication-overuse headache and opioid-induced hyperalgesia: A review of mechanisms, a neuroimmune hypothesis and a novel approach to treatment. Cephalalgia. 2013 Jan;33(1):52-64 PMID: https://www.ncbi.nlm.nih.gov/pubmed/23144180
- ↑ Carlsen LN, Rouw C, Westergaard ML et al Treatment of Medication Overuse Headache: Effect and Predictors After 1 Year. Headache. 2021;61(7):1112-1122 PMID: https://www.ncbi.nlm.nih.gov/pubmed/34325483 https://www.medscape.com/viewarticle/956376