fenfluramine (Pondimin, Ponderil, Ponderex, Adipomin, Fintepla)

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Introduction

Tradename: Pondimin. DEA-controlled substance: class 2. DEA-controlled substance: class 4[3].

Withdrawn from US market in 1997 following case reports of heart valve abnormalities in patients using flenfluramine or dexfenfluramine for appetite suppression[3].

Indications

Dosage

Tabs: 20 mg.

Pharmacokinetics

elimination via kidney

1/2life = 11-30 hours

Adverse effects

Drug interactions

Mechanism of action

More general terms

More specific terms

Component of

References

  1. The Pharmacological Basis of Therapeutics, 9th ed. Gilman et al, eds. Permagon Press/McGraw Hill, 1996
  2. Clinical Guide to Laboratory Tests, 3rd ed. Teitz ed., W.B. Saunders, 1995
  3. 3.0 3.1 3.2 Fresno Bee, Dec. 2000
  4. Harrison's Principles of Internal Medicine, 14th ed. Fauci et al (eds), McGraw-Hill Inc. NY, 1998, pg 461
  5. 5.0 5.1 Journal Watch 21(13):109, 2001 Davidoff et al, Arch Intern Med 161:1429, 2001
  6. 6.0 6.1 6.2 George J New Drug Approved for Rare Childhood Seizures - Fenfluramine reduced convulsive seizures in Dravet syndrome MedPage Today June 26, 2020 https://www.medpagetoday.com/washington-watch/fdageneral/87282

Database