fenfluramine/phentermine (fen-phen)
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Introduction
Taken off the market (1999) because of markedly increased risk of valvular heart disease & myocardial infarction.
Reference[2] &[3] suggest that the risk of valvular heart disease may have been initially overestimated.
More general terms
Components
- fenfluramine (Pondimin, Ponderil, Ponderex, Adipomin, Fintepla)
- phentermine (Fastin, Ionamin, Adipex)
References
- ↑ The Pharmacological Basis of Therapeutics, 9th ed. Gilman et al, eds. Permagon Press/McGraw Hill, 1996
- ↑ Jump up to: 2.0 2.1 Journal Watch vol 19 #22, pg 177, Nov 15, 1999
- ↑ Jump up to: 3.0 3.1 Burger et al J Am Coll Cardiol 34:1153, 1999