dexfenfluramine (Redux)

Introduction

Tradename: Redux. DEA-controlled substance: class 2. DEA-controlled substance: class 4.

FDA approved in 1996.

Withdrawn from US market is 1997.

Indications

obesity

Dosage

15 mg PO BID with meals

Tabs: 15 mg.

Pharmacokinetics

• eliminated by liver
• 1/2life: 11-30 hours

elimination via liver

1/2life = 11-30 hours

Adverse effects

pulmonary hypertension (23-46/100,000)

• drug adverse effects of analeptics
• drug adverse effects of psychotropic agents
• drug adverse effects of sympathomimetic(s)

More general terms

• fenfluramine (Pondimin, Ponderil, Ponderex, Adipomin, Fintepla)

Database

• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=65801
• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=66264