guaifenesin (Robitussin, Fenesin, Humibid LA, Mucinex)

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[1][2][3][4][5][6][7][8]

Introduction

Tradenames: Robitussin, Fenesin, Humibid LA.

Indications

Contraindications

pregnancy category = c

safety in lactation = ?

Dosage

  • adults & children > 12 years of age
    • 5-20 mL PO every 4 hours
    • 600-1200 mg PO every 12 hours
    • maximum 2400 mg QD
  • children 6-12 years of age
    • 5-10 mL/dose
    • 600 mg PO every 12 hours
    • maximum 1200 mg QD
  • children 2-6 years of age
  • increase fluid intake to help loosen mucus Tabs (sustained-release): 600 mg Mucinex (OTC)

Syrup: 100 mg/5 mL.

Adverse effects

Mechanism of action

  • expectorant action through increased output of respiratory fluid, enhancing flow of less viscid secretion
  • evidence is subjective & not well established

More general terms

Component of

References

  1. ↑ The Pharmacological Basis of Therapeutics, 9th ed. Gilman et al, eds. Permagon Press/McGraw Hill, 1996
  2. ↑ Drug Information & Medication Formulary, Veterans Affairs, Central California Health Care System, 1st ed., Ravnan et al eds, 1998
  3. ↑ Kaiser Permanente Northern California Regional Drug Formulary, 1998
  4. ↑ Jump up to: 4.0 4.1 Prescriber's Letter 7(12):67 2000
  5. ↑ Prescriber's Letter 9(9):53 2002
  6. ↑ Prescriber's Letter 11(1):3 2004 Detail-Document#: http://prescribersletter.com/(5bhgn1a4ni4cyp2tvybwfh55)/pl/ArticleDD.aspx?li=1&st=1&cs=&s=PRL&pt=3&fpt=25&dd=200102&pb=PRL (subscription needed) http://www.prescribersletter.com
  7. ↑ Prescriber's Letter 14(7): 2007 Unapproved Timed-release Guaifenesin Products Detail-Document#: http://prescribersletter.com/(5bhgn1a4ni4cyp2tvybwfh55)/pl/ArticleDD.aspx?li=1&st=1&cs=&s=PRL&pt=3&fpt=25&dd=230706&pb=PRL (subscription needed) http://www.prescribersletter.com
  8. ↑ Jump up to: 8.0 8.1 8.2 8.3 8.4 Deprecated Reference

Database

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