glutamate carboxypeptidase 2; glutamate carboxypeptidase-2; membrane glutamate carboxypeptidase; mGCP; N-acetylated-alpha-linked acidic dipeptidase 1; NAALADase 1; pteroylpoly-gamma-glutamate carboxypeptidase; folylpoly-gamma-glutamate carboxypeptidase; FGCP; folate hydrolase 1; prostate-specific membrane antigen; PSMA; PSM (FOLH1, FOLH, NAALAD1, PSM, PSMA, GCP2)

From Aaushi
Jump to navigation Jump to search

Function

pH dependence: stable at pH > 6.5

Cofactor:

  • binds 2 Zn+2 per subunit
  • Zn+2 required for NAALADase activity

Structure

Compartment

Alternative splicing

named isoforms=6 PSMA-1, PSMA-2, PSMA-3, PSMA-4, PSMA-5, PSMA'

Expression

Pathology

Polymorphism

More general terms

References

Database