CDK7/cyclin H complex, CDK-activating kinase (CAK) or p34cdc2 activating kinase

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Function

Structure

  • mammalian CAK appears to contain a 3rd subunit[2]

More general terms

References

  1. Solomon MJ. The function(s) of CAK, the p34cdc2-activating kinase. Trends Biochem Sci. 1994 Nov;19(11):496-500. PMID: https://www.ncbi.nlm.nih.gov/pubmed/7855894
  2. 2.0 2.1 Morgan DO. Principles of CDK regulation. Nature. 1995 Mar 9;374(6518):131-4. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/7877684 (review CDK regulation)
  3. 3.0 3.1 Shiekhattar R, Mermelstein F, Fisher RP, Drapkin R, Dynlacht B, Wessling HC, Morgan DO, Reinberg D. Cdk-activating kinase complex is a component of human transcription factor TFIIH. Nature. 1995 Mar 16;374(6519):283-7. PMID: https://www.ncbi.nlm.nih.gov/pubmed/7533895 (presence in TFIIH)
  4. 4.0 4.1 Dynlacht BD. Regulation of transcription by proteins that control the cell cycle. Nature. 1997 Sep 11;389(6647):149-52. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/9296491
  5. UniProt http://www.uniprot.org/uniprot/P51946.html