gamma-aminobutyric acid receptor-associated protein; GABA(A) receptor-associated protein; MM46 (GABARAP, FLC3B, HT004)

Function

• intracellular transport of GABA-A receptors
• interaction with the cytoskeleton
• role in apoptosis
• interacts with GPHN, NSF, GABRG2, beta-tubulin, ULK1
• interacts with CALR
• interacts with DDX47
• interacts with TP53INP1 & TP53INP2
• interacts with TBC1D25

Structure

belongs to the MAP1 LC3 family

Compartment

• cytoplasm, cytoskeleton
• endomembrane system, Golgi, post-synaptic cisternae
• cytoplasmic vesicle, autophagosome
• colocalizes with microtubules

Expression

• expressed in heart, brain, placenta, liver, skeletal muscle, kidney, pancreas

More general terms

• cytoskeletal protein

Additional terms

• GABA-A receptor
• gamma-aminobutyric acid receptor-associated protein-like 1; early estrogen-regulated protein; GABA(A) receptor-associated protein-like 1; glandular epithelial cell protein 1; GEC-1 (GABARAPL1, GEC1)

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=11337
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:11337
• OMIM: https://mirror.omim.org/entry/605125
• UniProt: http://www.uniprot.org/uniprot/O95166.html