histone H2A type 2-C (H2A-GL101, H2A/r, HIST2H2AC, H2AFQ)

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Function

chromatin-associated form is phosphorylated on Thr-120 during mitosis
deiminated on Arg-3 in granulocytes upon Ca+2 entry
monoubiquitination of Lys-119 by RING1 & RNF2/RING2 complex tags for epigenetic transcriptional repression & participates in X chromosome inactivation in females
role in initiation of both imprinted & random X inactivation
ubiquitinated H2A is enriched in inactive X chromosome
ubiquitination of H2A functions downstream of methylation of Lys-27 of histone H3
monoubiquitination of Lys-119 by RNF2/RING2 can also be induced by ultraviolet & may be involved in DNA repair
phosphorylation on Ser-1 is enhanced during mitosis
phosphorylation on Ser-1 by RPS6KA5/MSK1 directly represses transcription
acetylation of H3 inhibits Ser-1 phosphorylation by RPS6KA5/MSK1
symmetric dimethylation on Arg-3 by the PRDM1/PRMT5 complex may play a role in germ-cell lineage