zinc finger MYM-type protein 4; zinc finger protein 262 (ZMYM4, KIAA0425, ZNF262)

Function

• phosphorylated upon DNA damage, probably by ATM or ATR

Structure

contains 9 MYM-type zinc fingers

Alternative splicing

named isoforms=4

Expression

• expressed at higher level in heart, skeletal muscle, kidney & liver

Genetics

• gene prediction based on EST data
• 3'-UTR region of the mRNA encoding this protein
• contains a motif called CDIR (for cell death inhibiting RNA) that binds HNRPD/AUF1 & HSPB1/HSP27; it is able to inhibit interferon-gamma induced apoptosis

More general terms

• zinc finger protein
• phosphoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=9202
• UniProt: http://www.uniprot.org/uniprot/Q5VZL5.html