exosome component 7 (exosome complex exonuclease RRP42, ribosomal RNA processing protein 42, p8, EXOSC7, KIAA0116)

Function

• component of the exosome 3'->5' exoribonuclease complex
• also associated with the GTPase Ran
• interacts directly with EXOSC1, EXOSC6 & EXOSC8

Structure

belongs to the Rnase PH family

Compartment

nucleus, nucleolus

More general terms

• protein subunit
• nuclear protein

Component of

• exosome multienzyme ribonuclease complex

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:2301
• OMIM: https://mirror.omim.org/entry/606488
• UniProt: http://www.uniprot.org/uniprot/Q15024.html