exosome component 8 (exosome complex exonuclease RRP43, ribosomal RNA processing protein 43, p9, Opa-interacting protein 2, OIP2, EXOSC8)

Function

• component of the exosome 3'->5' exoribonuclease complex
• also associated with the GTPase Ran
• binds outer membrane protein opap from Neisseria gonorrhoeae

Structure

belongs to the Rnase PH family

Compartment

cytoplasm (putative), nucleus, nucleolus (putative)

More general terms

• protein subunit
• nuclear protein

Component of

• exosome multienzyme ribonuclease complex

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:1134
• OMIM: https://mirror.omim.org/entry/606019
• UniProt: http://www.uniprot.org/uniprot/Q96B26.html