transcription initiation factor TFIID subunit 9B; neuronal cell death-related protein 7; DN-7; transcription initiation factor TFIID subunit 9-like; transcription-associated factor TAFII31L (TAF9B, TAF9L)

Function

• essential for cell viability
• TAF9 & TAF9B are involved in transcriptional activation & transcriptional repression of distinct but overlapping sets of genes
• role in gene regulation associated with apoptosis
• TAFs are components of
  • TFIID complex
  • TBP-free TAFII complex (TFTC)
  • PCAF histone acetylase complex
  • STAGA transcription coactivator-HAT complex
• binds TAF5 & TAF6
• binds N-terminal domain of TP53/p53

Structure

belongs to the TAF9 family

Compartment

nucleus

More general terms

• protein subunit
• phosphoprotein

Component of

• transcription factor IID (TFIID)

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=51616
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:51616
• OMIM: https://mirror.omim.org/entry/300754
• UniProt: http://www.uniprot.org/uniprot/Q9HBM6.html