PDZ domain-containing protein GIPC1; GAIP C-terminus-interacting protein; RGS-GAIP-interacting protein; RGS19-interacting protein 1; Tax interaction protein 2; TIP-2 (GIPC1, C19orf3, GIPC, RGS19IP1)

Function

• may be involved in G protein-linked signaling
• interacts with GLUT1 (C-terminus), ACTN1, KIF1B, MYO6, PLEKHG5, SDC4/syndecan-4 & SEMA4C/semaphorin-4C (putative)
• interacts with RGS19 C-terminus.
• interacts with HTLV-I Tax through the PDZ domain

Structure

• belongs to the GIPC family
• contains 1 PDZ domain (DHR domain)

Compartment

• cytoplasm, peripheral membrane

Expression

widely expressed

More general terms

• other protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=10755
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:10755
• OMIM: https://mirror.omim.org/entry/605072
• UniProt: http://www.uniprot.org/uniprot/O14908.html