semaphorin-4C (SEMA4C KIAA1739 SEMAI UNQ5855/PRO34487)

Function

• probable signaling receptor which may play a role in myogenic differentiation through activation of the stress-activated MAPK cascade
• interacts (via PDZ-binding motif) with GIPC (via PDZ domain) (putative)
• interacts with NCDN
• interacts (via the PDZ-binding motif) with DLG4 (putative)

Structure

• belongs to the semaphorin family
• contains 1 Ig-like C2-type domain (immunoglobulin-like)
• contains 1 PSI domain
• contains 1 sema domain

Compartment

• cell junction, synapse, postsynaptic cell membrane, postsynaptic density; single-pass type 1 membrane protein (putative)
• cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; single-pass type 1 membrane protein

More general terms

• secreted protein
• glycoprotein
• semaphorin or semaphorin/collapsin family protein
• phosphoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=54910
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:54910
• OMIM: https://mirror.omim.org/entry/604462
• UniProt: http://www.uniprot.org/uniprot/Q9C0C4.html