PDZ (PSD-95 post-synaptic density protein, Discs large, Zona occludens tight junction protein) recognition motif
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Introduction
C-terminal motif of glutamate receptor epsilon subunits. This motif binds to PDZ domains of scaffold proteins.
The consensus sequence is [E/Q][S/T]XV.
More general terms
Additional terms
References
- ↑ Sheng M. Molecular organization of the postsynaptic specialization. Proc Natl Acad Sci U S A. 2001 Jun 19;98(13):7058-61. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/11416187
- ↑ Lim IA, Hall DD, Hell JW. Selectivity and promiscuity of the first and second PDZ domains of PSD-95 and synapse-associated protein 102. J Biol Chem. 2002 Jun 14;277(24):21697-711. Epub 2002 Apr 5. PMID: https://www.ncbi.nlm.nih.gov/pubmed/11937501